Bone fixation of implants during the early phases of healing is important for secondary stability of the implant assuring the success of the treatment. Because the placement of successful implant is limited by the quality and quantity of bone,
the
necessity of developing agents which stimulate bone formation in the peri-implant spaces has been illustrated. Certain polypeptied growth factors, such as, Platelet Derived Growth Factor, Fibroblast Growth Factor, Transforming Growth Factor, and
Insulin-like Growth Factor are known to be potent stimulators of healing process in vitro and in vivo.
@ES The results were as follows:
@EN 1. Bone formation was observed at 1 week in the control and experimental groups, but was not remarkable.
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